|
KMID : 0378120020290020091
|
|
Chungnam Medical Journal
2002 Volume.29 No. 2 p.91 ~ p.97
|
|
|
Atypical Antipsychotic Drugs and Glucose Dysregulation.
|
|
Lee Sun-Woo
|
|
|
Abstract
|
|
|
|
Evaluate glucose dysregulation in patients who are medicated with atypical antipsychotics. 31 subjects were enrolled by random selcetion. Subjects had a psychiatric interview including completion of various socio-demographic variables and a disease-related variable. Blood glucose levels. HbAlc level. and liver enzyme series(AST. ALT etc) were assessed. In 3 of 28 cases. new-onset. marked glucose intolerance developed and 3 of the 28 had impaired fasting glycemia after treatment with atypical antipsy- chotics. There were significant differences in liver enzyme (AST. ALT) levels and the total cholesterol level between the normal subjects group and the glucose dysregulation group. Atypical antipsychotics may he associated with nev-onset glucose intolerance. Therefore. monitoring for changes in blood glucose levels in patients taking atypical antipsychotics may be indicated. More systematic study data are clearly needed.
|
|
|
KEYWORD
|
|
|
Atypical Antipsychotics, Glucose Dysregulation
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|